Info
| ID | 6525 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 1} |
| Abbreviation | 2 |
| SMILES | Cc1ccc(C(C)C)cc1.Cc1ccnc(C(=O)[O-])c1.[Cl-] |
TUCAN
C17ClNO2Os/(1-14)(2-13)(3-12)(4-14)(5-8)(5-13)(6-12)(6-15)(7-9)(7-13)(8-11)(9-11)(10-12)(10-16)(11-14)(15-18)(16-17)(16-18)(17-19)(17-20)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 7.6 | — | 10.1021/jm901556u | 2009 |
🧬 Cell Death Types (1)
Apoptosis
medium
«We can therefore conclude that osmium complex 3 and probably the other structurally similar osmium complexes induce cell death via apoptotic pathways rather than necrosis.»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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