Info
| ID | 6524 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 1} |
| Abbreviation | 1 |
| SMILES | Cc1ccnc(C(=O)[O-])c1.[Cl-].c1ccccc1 |
TUCAN
C13ClNO2Os/(1-10)(2-4)(2-5)(3-10)(3-12)(4-6)(5-7)(6-8)(7-8)(9-10)(9-11)(11-14)(12-13)(12-14)(13-15)(13-16)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 33 | — | 10.1021/jm901556u | 2009 |
🧬 Cell Death Types (1)
Apoptosis
medium
«We can therefore conclude that osmium complex 3 and probably the other structurally similar osmium complexes induce cell death via apoptotic pathways rather than necrosis.»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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