Info
| ID | 6509 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 3} |
| Abbreviation | 4 |
| SMILES | Cc1ccc(C(C)C)cc1.Oc1ccc(/N=N/c2ccccn2)cc1.[I-] |
TUCAN
C21H23N3OOs/(1-30)(2-24)(3-37)(4-25)(5-24)(6-24)(7-28)(8-33)(9-27)(10-41)(11-29)(12-36)(13-35)(14-34)(15-31)(16-25)(17-25)(18-26)(19-32)(20-26)(21-40)(22-26)(23-48)(24-38)(25-40)(26-40)(27-28)(27-42)(28-44)(29-35)(29-42)(30-31)(30-38)(31-39)(32-37)(32-39)(33-34)(33-36)(34-41)(35-44)(36-43)(37-38)(39-40)(41-45)(42-47)(43-45)(43-46)(44-48)(46-47)(46-49)(47-49)(48-49)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 0.32 | — | 10.1021/jm100560f | 2010 |
| A2780 | 0.51 | — | 10.1039/d1qi00512j | 2021 |
| MRC-5 | 0.69 | — | 10.1039/d1qi00512j | 2021 |
| PC-3 | 0.91 | — | 10.1039/d1qi00512j | 2021 |
| A549 | 0.94 | — | 10.1039/d1qi00512j | 2021 |
🧬 Cell Death Types (1)
Apoptosis
medium
«Cellular alterations observed included membrane blebbing and the collapse of nuclear integrity, suggesting the initiation of programmed cell death pathways, as previously reported from XRF studies usi...»
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