Info
| ID | 6493 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 6} |
| Abbreviation | Os1 |
| SMILES | CCCCn1c(-c2[c-]cccc2)nc2cc(C(=O)OC)ccc21.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C39H35N6O2Os/(1-42)(2-38)(3-39)(4-43)(5-44)(6-51)(7-73)(8-73)(9-73)(10-45)(11-46)(12-47)(13-61)(14-62)(15-36)(16-36)(17-36)(18-65)(19-65)(20-40)(21-52)(22-54)(23-49)(24-55)(25-48)(26-57)(27-57)(28-41)(29-53)(30-63)(31-50)(32-56)(33-64)(34-58)(35-58)(36-58)(37-54)(37-60)(38-44)(38-66)(39-46)(39-67)(40-42)(40-52)(41-53)(41-68)(42-60)(43-44)(43-61)(45-46)(45-62)(47-48)(47-63)(48-55)(49-50)(49-64)(50-56)(51-59)(51-71)(52-54)(53-59)(55-69)(56-70)(57-58)(57-65)(59-74)(60-72)(61-76)(62-77)(63-78)(64-79)(65-75)(66-67)(66-76)(67-77)(68-71)(68-75)(69-70)(69-78)(70-79)(71-80)(72-75)(72-80)(73-82)(74-81)(74-82)(76-83)(77-83)(78-83)(79-83)(80-83)(82-83)
Measurements (9)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| PNT1A | 0.19 | — | 10.1021/acs.inorgchem.3c00501 | 2023 |
| MCF-7 | 0.23 | — | 10.1021/acs.inorgchem.3c00501 | 2023 |
| MDA-MB-231 | 0.26 | — | 10.1021/acs.inorgchem.3c00501 | 2023 |
| HCT-116 | 0.3 | — | 10.1021/acs.inorgchem.3c00501 | 2023 |
| OE33 | 0.31 | — | 10.1021/acs.inorgchem.3c00501 | 2023 |
| PSN1 | 0.37 | — | 10.1021/acs.inorgchem.3c00501 | 2023 |
| A375 | 0.43 | — | 10.1021/acs.inorgchem.3c00501 | 2023 |
| MRC5pd30 | 0.46 | — | 10.1021/acs.inorgchem.3c00501 | 2023 |
| HeLa | 0.9 | — | 10.1021/acs.inorgchem.3c00501 | 2023 |