Info
| ID | 6487 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | 5 |
| SMILES | Cc1ccc(S(=O)(=O)[N-][C@H](c2ccccc2)[C@H]([N-]CCCc2ccccc2)c2ccccc2)cc1 |
TUCAN
C30H30N2O2OsS/(1-52)(2-40)(3-51)(4-34)(5-35)(6-33)(7-36)(8-39)(9-41)(10-44)(11-57)(12-48)(13-37)(14-59)(15-42)(16-32)(17-43)(18-52)(19-51)(20-46)(21-38)(22-31)(23-49)(24-45)(25-47)(26-31)(27-31)(28-50)(29-57)(30-58)(31-53)(32-34)(32-39)(33-35)(33-60)(34-36)(35-53)(36-56)(37-48)(37-53)(38-49)(38-50)(39-41)(40-49)(40-55)(41-56)(42-43)(42-54)(43-44)(44-45)(45-46)(46-54)(47-50)(47-55)(48-60)(51-52)(51-57)(52-54)(55-58)(56-59)(57-61)(58-59)(58-62)(59-61)(60-65)(61-66)(62-65)(62-66)(63-65)(64-65)
Measurements (7)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 8.1 | — | 10.1002/cbic.202400374 | 2024 |
| MCF7−TAMR-1 | 9 | — | 10.1002/cbic.202400374 | 2024 |
| MDA-MB-231 | 9.1 | — | 10.1002/cbic.202400374 | 2024 |
| A2780 | 10 | — | 10.1002/cbic.202400374 | 2024 |
| A549 | 14 | — | 10.1002/cbic.202400374 | 2024 |
| MCF-10A | 31 | — | 10.1002/cbic.202400374 | 2024 |
| HCT-116 | 36 | — | 10.1002/cbic.202400374 | 2024 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.