Info
| ID | 6486 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | 4 |
| SMILES | Cc1ccc(C(C)C)cc1.Cc1ccc(S(=O)(=O)[N-][C@H](c2ccccc2)[C@H]([NH-])c2ccccc2)cc1 |
TUCAN
C31H34N2O2OsS/(1-48)(2-41)(3-63)(4-36)(5-45)(6-35)(7-35)(8-47)(9-36)(10-42)(11-64)(12-44)(13-40)(14-43)(15-49)(16-53)(17-50)(18-51)(19-56)(20-38)(21-39)(22-52)(23-38)(24-38)(25-55)(26-36)(27-37)(28-46)(29-37)(30-62)(31-35)(32-54)(33-37)(34-66)(35-58)(36-62)(37-62)(38-61)(39-44)(39-53)(40-43)(40-61)(41-42)(41-52)(42-48)(43-65)(44-49)(45-47)(45-58)(46-54)(46-58)(47-60)(48-57)(49-59)(50-53)(50-59)(51-52)(51-57)(54-60)(55-56)(55-65)(56-61)(57-64)(59-63)(60-62)(63-64)(63-66)(64-67)(65-70)(66-71)(67-70)(67-71)(68-70)(69-70)
Measurements (12)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 11 | — | 10.1002/cbic.202400374 | 2024 |
| MDA-MB-231 | 15 | — | 10.1002/cbic.202400374 | 2024 |
| A2780 | 16 | — | 10.1002/cbic.202400374 | 2024 |
| A2780 | 16 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| A549 | 21 | — | 10.1002/cbic.202400374 | 2024 |
| A549 | 21 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| MRC-5 | 21 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| A2780cisR | 22 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| HOF | 30 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| HCT-116 | 37 | — | 10.1002/cbic.202400374 | 2024 |
| HCT-116 | 37 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| HCT-116Ox | 51 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.