Info
| ID | 6476 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | Os3 |
| SMILES | Cc1ccc(C(C)C)cc1.FC(F)(F)c1ccc(-n2cc(-c3nc4ccccc4s3)nn2)cc1.[Cl-] |
TUCAN
C26H23F3N4OsS/(1-32)(2-24)(3-33)(4-25)(5-38)(6-24)(7-31)(8-30)(9-36)(10-35)(11-28)(12-27)(13-37)(14-29)(15-43)(16-25)(17-25)(18-34)(19-26)(20-24)(21-26)(22-26)(23-42)(24-40)(25-42)(26-42)(27-29)(27-45)(28-31)(28-39)(29-36)(30-36)(30-48)(31-44)(32-33)(32-40)(33-41)(34-38)(34-41)(35-37)(35-44)(37-39)(38-40)(39-47)(41-42)(43-46)(43-50)(44-50)(45-48)(45-52)(46-49)(46-53)(47-54)(47-55)(47-56)(48-57)(49-52)(49-57)(50-51)(51-53)(52-58)(53-58)(57-58)
Measurements (7)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| RD | 24 | — | 10.1039/d4qi02737j | 2025 |
| HCT-116 | 34 | — | 10.1039/d4qi02737j | 2025 |
| MDA-MB-231 | 40 | — | 10.1039/d4qi02737j | 2025 |
| HeLa | 43 | — | 10.1039/d4qi02737j | 2025 |
| MCF-7 | 45 | — | 10.1039/d4qi02737j | 2025 |
| PSN1 | 47 | — | 10.1039/d4qi02737j | 2025 |
| MRC-5 | 76 | — | 10.1039/d4qi02737j | 2025 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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