Info
| ID | 6465 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | 1 |
| SMILES | CN(C)c1ccc(/N=N/c2ccccn2)cc1.Cc1ccc(C(C)C)cc1.[I-] |
TUCAN
C23H28N4Os/(1-45)(2-29)(3-33)(4-29)(5-29)(6-37)(7-32)(8-31)(9-30)(10-31)(11-31)(12-38)(13-42)(14-35)(15-34)(16-46)(17-46)(18-46)(19-47)(20-41)(21-47)(22-48)(23-30)(24-30)(25-36)(26-40)(27-39)(28-47)(29-45)(30-44)(31-45)(32-33)(32-44)(33-43)(34-35)(34-50)(35-49)(36-37)(36-44)(37-43)(38-41)(38-42)(39-40)(39-49)(40-50)(41-48)(42-51)(43-45)(46-53)(47-53)(48-52)(49-55)(50-53)(51-52)(51-54)(54-55)(54-56)(55-56)
Measurements (14)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 0.12 | — | 10.1073/pnas.1500925112 | 2015 |
| A2780 | 0.15 | — | 10.1073/pnas.1500925112 | 2015 |
| A2780 | 0.18 | — | 10.1021/jm100560f | 2010 |
| MCF-7 | 0.2 | — | 10.1021/jm100560f | 2010 |
| A2780 | 0.2 | — | 10.1039/c1md00075f | 2011 |
| HCT-116 | 0.22 | — | 10.1021/jm100560f | 2010 |
| A2780cisR | 0.23 | — | 10.1021/jm100560f | 2010 |
| RT-112 | 0.25 | — | 10.1021/jm100560f | 2010 |
| HCT-116 | 0.26 | — | 10.1073/pnas.1500925112 | 2015 |
| A549 | 0.28 | — | 10.1073/pnas.1500925112 | 2015 |
| A549 | 0.38 | — | 10.1021/jm100560f | 2010 |
| A549 | 0.4 | — | 10.1039/c1md00075f | 2011 |
| PC-3 | 0.62 | — | 10.1021/jm100560f | 2010 |
| PC-3 | 0.65 | — | 10.1073/pnas.1500925112 | 2015 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.