Info
| ID | 6446 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 2, "P": 1} |
| Abbreviation | 1c |
| SMILES | S=C(Nc1ccc(Cl)cc1)c1ccccn1.c1ccc(-c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C42H34ClN2OsPS/(1-37)(2-39)(3-38)(4-47)(5-35)(6-36)(7-40)(8-41)(9-51)(10-55)(11-63)(12-66)(13-62)(14-44)(15-45)(16-58)(17-53)(18-43)(19-46)(20-42)(21-49)(22-60)(23-50)(24-57)(25-52)(26-56)(27-59)(28-65)(29-64)(30-54)(31-48)(32-61)(33-69)(34-77)(35-37)(35-38)(36-38)(36-39)(37-72)(39-72)(40-47)(40-53)(41-43)(41-45)(42-45)(42-46)(43-67)(44-49)(44-70)(46-67)(47-73)(48-57)(48-68)(49-76)(50-60)(50-76)(51-55)(51-73)(52-58)(52-74)(53-55)(54-58)(54-59)(56-59)(56-74)(57-65)(60-70)(61-64)(61-68)(62-63)(62-69)(63-66)(64-65)(66-71)(67-68)(69-78)(70-77)(71-75)(71-78)(72-79)(73-79)(74-79)(75-77)(75-80)(76-81)(78-82)(79-82)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HCT-116 | 0.78 | — | 10.1016/j.jinorgbio.2022.11211... | 2023 |
| SiHa | 0.94 | — | 10.1016/j.jinorgbio.2022.11211... | 2023 |
| SW480 | 1 | — | 10.1016/j.jinorgbio.2022.11211... | 2023 |
| NCI-H460 | 1.1 | — | 10.1016/j.jinorgbio.2022.11211... | 2023 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.