Info
| ID | 6331 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"N": 4, "O": 3} |
| Abbreviation | 5 |
| SMILES | Clc1ccc2c(NCCC/N=C/c3ccc4ccccc4n3)ccnc2c1.[C-]#[O+].[C-]#[O+].[C-]#[O+].[Cl-] |
TUCAN
C25H19ClN4O3Re/(1-20)(2-29)(3-35)(4-27)(5-22)(6-36)(7-36)(8-30)(9-26)(10-35)(11-24)(12-30)(13-33)(14-34)(15-28)(16-21)(17-23)(18-25)(19-46)(20-33)(20-39)(21-23)(21-38)(22-37)(22-44)(23-25)(24-27)(24-32)(25-26)(26-32)(27-40)(28-29)(28-31)(29-44)(30-35)(30-36)(31-37)(31-39)(32-38)(33-45)(34-40)(34-48)(35-46)(36-48)(37-45)(38-47)(39-46)(40-47)(41-49)(42-50)(43-51)(44-52)(47-53)(48-53)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 6.8 | — | 10.1016/j.ejmech.2023.116094 | 2024 |
| MDA-MB-231 | 11 | — | 10.1016/j.ejmech.2023.116094 | 2024 |
| FG0 | 11 | — | 10.1016/j.ejmech.2023.116094 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Moreover, apoptosis was confirmed in both cell lines due to the detection of cleaved PARP.»