Info
| ID | 6330 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"N": 4, "O": 3} |
| Abbreviation | 4 |
| SMILES | Clc1ccc2c(NCCC/N=C/c3ccccn3)ccnc2c1.[C-]#[O+].[C-]#[O+].[C-]#[O+].[Cl-] |
TUCAN
C21H17ClN4O3Re/(1-19)(2-29)(3-18)(4-25)(5-23)(6-31)(7-25)(8-20)(9-30)(10-30)(11-27)(12-31)(13-24)(14-28)(15-21)(16-22)(17-40)(18-32)(18-38)(19-27)(19-33)(20-22)(20-34)(21-22)(21-28)(23-24)(23-26)(24-38)(25-30)(25-31)(26-32)(26-33)(27-39)(28-41)(29-34)(29-42)(30-40)(31-42)(32-39)(33-40)(34-41)(35-43)(36-44)(37-45)(38-46)(41-47)(42-47)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| FG0 | 7.1 | — | 10.1016/j.ejmech.2023.116094 | 2024 |
| MCF-7 | 8.6 | — | 10.1016/j.ejmech.2023.116094 | 2024 |
| MDA-MB-231 | 18 | — | 10.1016/j.ejmech.2023.116094 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Moreover, apoptosis was confirmed in both cell lines due to the detection of cleaved PARP.»