Info
| ID | 6296 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 2 |
| Donor atoms | {"N": 4, "O": 1} |
| Abbreviation | 3 |
| SMILES | NC(=[NH2+])Nc1cccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)c1.[C-]#[O+].[C-]#[O+].[C-]#[O+].c1c[nH]cn1 |
TUCAN
C26H20N9O3Re/(1-21)(2-24)(3-35)(4-23)(5-26)(6-32)(7-25)(8-34)(9-41)(10-33)(11-28)(12-27)(13-22)(14-47)(15-51)(16-47)(17-52)(18-48)(19-48)(20-50)(21-30)(21-37)(22-23)(22-29)(23-32)(24-25)(24-34)(25-31)(26-27)(26-28)(27-37)(28-30)(29-36)(29-38)(30-42)(31-39)(31-40)(32-49)(33-35)(33-50)(34-53)(35-55)(36-39)(36-51)(37-52)(38-40)(38-49)(39-54)(40-53)(41-50)(41-55)(42-51)(42-54)(43-47)(43-48)(43-52)(44-56)(45-57)(46-58)(53-59)(54-59)(55-59)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 13 | — | 10.1007/s00775-020-01827-7 | 2020 |
| A549 | 29 | — | 10.1007/s00775-020-01827-7 | 2020 |
| MCF-7 | 40 | — | 10.1007/s00775-020-01827-7 | 2020 |
| HeLa | 45 | — | 10.1007/s00775-020-01827-7 | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«The ability of complex 3 inducing apoptosis of HepG2 cells was investigated by Hoechst 33342 and Annexin V/PI labeling.»