Info
| ID | 6295 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 2 |
| Donor atoms | {"N": 4, "O": 1} |
| Abbreviation | 2 |
| SMILES | NC(=[NH2+])Nc1cccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)c1.[C-]#[O+].[C-]#[O+].[C-]#[O+].c1ccncc1 |
TUCAN
C28H21N8O3Re/(1-24)(2-30)(3-22)(4-32)(5-39)(6-23)(7-25)(8-28)(9-31)(10-27)(11-29)(12-36)(13-37)(14-38)(15-26)(16-50)(17-50)(18-53)(19-54)(20-51)(21-51)(22-23)(22-36)(23-29)(24-28)(24-33)(25-34)(25-43)(26-31)(26-38)(27-32)(27-43)(28-39)(29-37)(30-32)(30-34)(31-35)(33-40)(33-41)(34-45)(35-42)(35-44)(36-55)(37-55)(38-56)(39-52)(40-44)(40-53)(41-42)(41-52)(42-56)(43-54)(44-57)(45-53)(45-57)(46-50)(46-51)(46-54)(47-58)(48-59)(49-60)(55-61)(56-61)(57-61)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 41 | — | 10.1007/s00775-020-01827-7 | 2020 |
| A549 | 50 | — | 10.1007/s00775-020-01827-7 | 2020 |
| MCF-7 | 53 | — | 10.1007/s00775-020-01827-7 | 2020 |
| HeLa | 88 | — | 10.1007/s00775-020-01827-7 | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«The ability of complex 3 inducing apoptosis of HepG2 cells was investigated by Hoechst 33342 and Annexin V/PI labeling.»