Info
| ID | 6294 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 1 |
| Donor atoms | {"N": 4, "O": 1} |
| Abbreviation | 1 |
| SMILES | NC(=[NH2+])Nc1cccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)c1.[C-]#[O+].[C-]#[O+].[C-]#[O+].[Cl-] |
TUCAN
C23H16N7O3Re/(1-17)(2-20)(3-19)(4-24)(5-21)(6-22)(7-18)(8-28)(9-29)(10-23)(11-40)(12-40)(13-41)(14-43)(15-41)(16-44)(17-19)(17-25)(18-27)(18-34)(19-28)(20-23)(20-26)(21-22)(21-24)(22-34)(23-29)(24-27)(25-30)(25-32)(26-31)(26-33)(27-35)(28-42)(29-45)(30-31)(30-42)(31-45)(32-33)(32-43)(33-46)(34-44)(35-43)(35-46)(36-40)(36-41)(36-44)(37-47)(38-48)(39-49)(45-50)(46-50)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 22 | — | 10.1007/s00775-020-01827-7 | 2020 |
| MCF-7 | 31 | — | 10.1007/s00775-020-01827-7 | 2020 |
| A549 | 47 | — | 10.1007/s00775-020-01827-7 | 2020 |
| HeLa | 1.9e+02 | — | 10.1007/s00775-020-01827-7 | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«The ability of complex 3 inducing apoptosis of HepG2 cells was investigated by Hoechst 33342 and Annexin V/PI labeling.»