Info
| ID | 6293 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 1 |
| Donor atoms | {"N": 4, "O": 3} |
| Abbreviation | [Re(CO)3(L2)]BF4 |
| SMILES | O=C1c2cccc3cc4ccccc4c(c23)C(=O)N1CCN(Cc1ccccn1)Cc1ccccn1.[C-]#[O+].[C-]#[O+].[C-]#[O+] |
TUCAN
C33H24N4O5Re/(1-47)(2-35)(3-33)(4-32)(5-31)(6-36)(7-38)(8-28)(9-26)(10-50)(11-50)(12-25)(13-47)(14-29)(15-34)(16-48)(17-49)(18-30)(19-37)(20-48)(21-45)(22-49)(23-46)(24-27)(25-26)(25-28)(26-45)(27-29)(27-46)(28-51)(29-30)(30-52)(31-38)(31-39)(32-34)(32-41)(33-39)(33-41)(34-37)(35-36)(35-38)(36-42)(37-40)(39-42)(40-43)(40-56)(41-43)(42-44)(43-44)(44-57)(45-60)(46-61)(47-51)(47-59)(48-50)(48-58)(49-52)(49-59)(50-59)(51-60)(52-61)(53-62)(54-65)(55-66)(56-58)(56-63)(57-58)(57-64)(60-67)(61-67)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| LoVo | 5.7 | — | 10.1002/ejic.201601271 | 2017 |
| A549 | 6 | — | 10.1002/ejic.201601271 | 2017 |
| MCF-7 | 6 | — | 10.1002/ejic.201601271 | 2017 |
| PC-3 | 6.3 | — | 10.1002/ejic.201601271 | 2017 |
🧬 Cell Death Types (1)
Apoptosis
medium
«Imaging of MCF7 cells with fac-[Re(CO)3(L1)]BF4 and fac-[Re(CO)3(L2)]BF4 showed that some of the stained cells had an unhealthy 'foamy' appearance with some membrane blebbing, indicating apoptosis.»