Info
| ID | 6292 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 1 |
| Donor atoms | {"N": 4, "O": 3} |
| Abbreviation | [Re(CO)3(L1)]BF4 |
| SMILES | O=C1c2cccc3cc4ccccc4c(c23)C(=O)N1CCCCCCN(Cc1ccccn1)Cc1ccccn1.[C-]#[O+].[C-]#[O+].[C-]#[O+] |
TUCAN
C37H32N4O5Re/(1-59)(2-50)(3-45)(4-48)(5-40)(6-48)(7-47)(8-50)(9-47)(10-35)(11-33)(12-62)(13-61)(14-44)(15-41)(16-61)(17-62)(18-34)(19-59)(20-42)(21-46)(22-38)(23-49)(24-60)(25-43)(26-36)(27-37)(28-49)(29-57)(30-60)(31-58)(32-39)(33-34)(33-57)(34-35)(35-63)(36-46)(36-51)(37-40)(37-53)(38-51)(38-53)(39-42)(39-58)(40-45)(41-44)(41-46)(42-43)(43-64)(44-56)(45-52)(47-48)(47-50)(48-61)(49-50)(49-62)(51-56)(52-54)(52-68)(53-54)(54-55)(55-56)(55-69)(57-72)(58-73)(59-63)(59-71)(60-64)(60-71)(61-70)(62-71)(63-72)(64-73)(65-74)(66-77)(67-78)(68-70)(68-75)(69-70)(69-76)(72-79)(73-79)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 6.2 | — | 10.1002/ejic.201601271 | 2017 |
| PC-3 | 7.5 | — | 10.1002/ejic.201601271 | 2017 |
| LoVo | 7.8 | — | 10.1002/ejic.201601271 | 2017 |
| A549 | 75 | — | 10.1002/ejic.201601271 | 2017 |
🧬 Cell Death Types (1)
Apoptosis
medium
«Imaging of MCF7 cells with fac-[Re(CO)3(L1)]BF4 and fac-[Re(CO)3(L2)]BF4 showed that some of the stained cells had an unhealthy 'foamy' appearance with some membrane blebbing, indicating apoptosis.»