Info
| ID | 6284 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 1 |
| Donor atoms | {"N": 3, "O": 3} |
| Abbreviation | fac-[Re(et-isonic)(Me2phen)(CO)3]+ |
| SMILES | CCOC(=O)c1ccncc1.Cc1ccnc2c1ccc1c(C)ccnc12.[C-]#[O+].[C-]#[O+].[C-]#[O+] |
TUCAN
C25H21N3O5Re/(1-22)(2-22)(3-22)(4-27)(5-26)(6-45)(7-30)(8-45)(9-24)(10-23)(11-36)(12-23)(13-38)(14-29)(15-24)(16-37)(17-24)(18-39)(19-23)(20-25)(21-28)(22-32)(23-33)(24-45)(25-28)(25-31)(26-35)(26-37)(27-32)(27-36)(28-34)(29-33)(29-38)(30-35)(30-39)(31-32)(31-40)(33-34)(34-41)(35-46)(36-47)(37-48)(38-49)(39-48)(40-41)(40-47)(41-49)(42-50)(43-52)(44-53)(45-54)(46-51)(46-54)(47-55)(48-55)(49-55)(54-55)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| SkMel-29 | 8.3 | — | 10.1016/j.ica.2019.119329 | 2020 |
| SK-MEL-147 | 9.9 | — | 10.1016/j.ica.2019.119329 | 2020 |
| MCF-7 | 29 | — | 10.1016/j.ica.2019.119329 | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«It is observed a shift of cell populations from control to the Ann+ quadrant for all tumor cell lines used after 24 hours of treatment... thereby indicating that these cells were in the process of dea...»