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Complex #6283 — Re(1) [fac-[Re(et-isonic)(phen)(CO)3]+]

2D Structure

Structure
⬇ MOL V3000

Info

ID6283
MetalRe
Oxidation state1
Charge1
Donor atoms{"N": 3, "O": 3}
Abbreviationfac-[Re(et-isonic)(phen)(CO)3]+
SMILESCCOC(=O)c1ccncc1.[C-]#[O+].[C-]#[O+].[C-]#[O+].c1cnc2c(c1)ccc1cccnc12

TUCAN

C23H17N3O5Re/(1-30)(2-31)(3-20)(4-23)(5-19)(6-39)(7-18)(8-18)(9-21)(10-22)(11-25)(12-24)(13-26)(14-33)(15-32)(16-39)(17-18)(18-39)(19-29)(19-30)(20-21)(20-31)(21-27)(22-25)(22-27)(23-24)(23-32)(24-28)(25-28)(26-29)(26-33)(27-34)(28-35)(29-40)(30-43)(31-41)(32-42)(33-43)(34-35)(34-41)(35-42)(36-44)(37-45)(38-46)(39-48)(40-47)(40-48)(41-49)(42-49)(43-49)(48-49)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
SK-MEL-14719 10.1016/j.ica.2019.119329 2020
SkMel-2919 10.1016/j.ica.2019.119329 2020
MCF-786 10.1016/j.ica.2019.119329 2020

🧬 Cell Death Types (1)

Apoptosis high
«It is observed a shift of cell populations from control to the Ann+ quadrant for all tumor cell lines used after 24 hours of treatment... thereby indicating that these cells were in the process of dea...»