Info
| ID | 6277 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"N": 2, "O": 3} |
| Abbreviation | 7b |
| SMILES | Cc1ccc(/N=C2/C=C(Cl)C=C/C2=N\O)cc1.[Br-].[C-]#[O+].[C-]#[O+].[C-]#[O+] |
TUCAN
C16H11ClN2O4Re/(1-12)(2-15)(3-16)(4-14)(5-12)(6-19)(7-12)(8-17)(9-13)(10-18)(11-33)(12-20)(13-18)(13-21)(14-15)(14-22)(15-20)(16-19)(16-20)(17-23)(17-27)(18-27)(19-22)(21-23)(21-29)(22-28)(23-28)(24-30)(25-31)(26-32)(27-34)(28-35)(29-33)(29-35)(33-35)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A375 | 1.8 | — | 10.1016/j.jinorgbio.2010.03.01... | 2010 |
| K-562 | 7.8 | — | 10.1016/j.jinorgbio.2010.03.01... | 2010 |
🧬 Cell Death Types (1)
Apoptosis
high
«Chlorido complexes (6a and 6c) were more efficient than bromido compounds (7d and 7b) in inducing apoptotic cell death of both types of cancer cells.»