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Complex #6276 — Re(1) [7d]

2D Structure

Structure
⬇ MOL V3000

Info

ID6276
MetalRe
Oxidation state1
Charge0
Donor atoms{"N": 2, "O": 3}
Abbreviation7d
SMILESO/N=C1\C=CC(Cl)=C\C1=N\c1ccccc1.[Br-].[C-]#[O+].[C-]#[O+].[C-]#[O+]

TUCAN

C15H9ClN2O4Re/(1-15)(2-10)(3-16)(4-11)(5-17)(6-12)(7-14)(8-13)(9-30)(10-11)(10-12)(11-18)(12-14)(13-14)(13-18)(15-19)(15-24)(16-17)(16-24)(17-20)(18-25)(19-20)(19-25)(20-26)(21-27)(22-28)(23-29)(24-31)(25-32)(26-30)(26-32)(30-32)

Measurements (2)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A3751.3 10.1016/j.jinorgbio.2010.03.01... 2010
K-5627.5 10.1016/j.jinorgbio.2010.03.01... 2010

🧬 Cell Death Types (1)

Apoptosis high
«Chlorido complexes (6a and 6c) were more efficient than bromido compounds (7d and 7b) in inducing apoptotic cell death of both types of cancer cells.»