Info
| ID | 6221 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"N": 3, "O": 3} |
| Abbreviation | H2Bnz2 |
| SMILES | O=C(N/N=C\c1ccccc1O)N(Cc1ccccc1)Cc1ccccc1.[Br-].[C-]#[O+].[C-]#[O+].[C-]#[O+] |
TUCAN
C25H21N3O5Re/(1-25)(2-22)(3-31)(4-24)(5-39)(6-40)(7-26)(8-30)(9-23)(10-27)(11-34)(12-35)(13-32)(14-40)(15-29)(16-28)(17-33)(18-41)(19-41)(20-48)(21-54)(22-24)(22-36)(23-26)(23-36)(24-25)(25-26)(27-30)(27-37)(28-29)(28-38)(29-35)(30-31)(31-32)(32-33)(33-37)(34-35)(34-45)(36-40)(37-41)(38-39)(38-45)(39-49)(40-47)(41-47)(42-50)(43-52)(44-53)(45-54)(46-47)(46-48)(46-51)(48-49)(49-55)(54-55)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 24 | — | 10.1016/j.jinorgbio.2012.10.01... | 2013 |
🧬 Cell Death Types (1)
Apoptosis
high
«Apoptotic assays of [ReBr(CO)3(H2Bnz2)] revealed that it mediates cytotoxicity in MOLT-4 cells via apoptosis. (Section 3.7: MOLT-4 cells treated with [ReBr(CO)3(H2Bnz2)] showed an increasing degree of...»