Info
| ID | 6214 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"N": 3, "O": 3} |
| Abbreviation | Re3 |
| SMILES | Nc1cc2cccnc2c2ncccc12.[C-]#[O+].[C-]#[O+].[C-]#[O+].[Cl-] |
TUCAN
C15H9N3O3Re/(1-12)(2-14)(3-18)(4-13)(5-10)(6-11)(7-17)(8-25)(9-25)(10-11)(10-15)(11-17)(12-14)(12-16)(13-16)(13-21)(14-18)(15-19)(15-21)(16-20)(17-26)(18-27)(19-20)(19-26)(20-27)(21-25)(22-28)(23-29)(24-30)(26-31)(27-31)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | — | 1.9 | 10.1021/acs.jmedchem.3c02485 | 2024 |
| MCF-7 | — | 8.8 | 10.1021/acs.jmedchem.3c02485 | 2024 |
| HEK293 | — | — | 10.1021/acs.jmedchem.3c02485 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«The cell death mechanism revealed that Re3 produced an apoptotic cell death response in HeLa cells via ROS generation.»