Info
| ID | 6213 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"O": 4, "N": 2} |
| Abbreviation | Re2 |
| SMILES | O=[N+]([O-])c1cc2cccnc2c2ncccc12.[C-]#[O+].[C-]#[O+].[C-]#[O+].[Cl-] |
TUCAN
C15H7N3O5Re/(1-9)(2-10)(3-11)(4-12)(5-16)(6-15)(7-8)(8-12)(8-15)(9-10)(9-16)(10-13)(11-14)(11-19)(12-14)(13-17)(13-19)(14-18)(15-25)(16-24)(17-18)(17-24)(18-25)(19-23)(20-26)(21-27)(22-28)(23-29)(23-30)(24-31)(25-31)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | — | 2 | 10.1021/acs.jmedchem.3c02485 | 2024 |
| MCF-7 | — | 9.2 | 10.1021/acs.jmedchem.3c02485 | 2024 |
| HEK293 | — | — | 10.1021/acs.jmedchem.3c02485 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«The cell death mechanism revealed that Re3 produced an apoptotic cell death response in HeLa cells via ROS generation.»