Info
| ID | 6212 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"O": 3, "N": 2} |
| Abbreviation | Re1 |
| SMILES | [C-]#[O+].[C-]#[O+].[C-]#[O+].[Cl-].c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C15H8N2O3Re/(1-10)(2-17)(3-18)(4-13)(5-14)(6-11)(7-9)(8-12)(9-12)(9-15)(10-13)(10-15)(11-14)(11-16)(12-16)(13-17)(14-18)(15-19)(16-20)(17-24)(18-25)(19-20)(19-24)(20-25)(21-26)(22-27)(23-28)(24-29)(25-29)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | — | — | 10.1021/acs.jmedchem.3c02485 | 2024 |
| MCF-7 | — | — | 10.1021/acs.jmedchem.3c02485 | 2024 |
| HEK293 | — | — | 10.1021/acs.jmedchem.3c02485 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«The cell death mechanism revealed that Re3 produced an apoptotic cell death response in HeLa cells via ROS generation.»