Info
| ID | 6201 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"O": 3, "N": 4} |
| Abbreviation | 3f |
| SMILES | [C-]#[O+].[C-]#[O+].[C-]#[O+].[Cl-].c1ccc2cc3c(-c4nc5c6cccnc6c6ncccc6c5[nH]4)cccc3cc2c1 |
TUCAN
C30H16N4O3Re/(1-25)(2-22)(3-37)(4-21)(5-38)(6-20)(7-23)(8-24)(9-17)(10-28)(11-18)(12-26)(13-27)(14-19)(15-29)(16-48)(17-23)(17-30)(18-24)(18-34)(19-25)(19-32)(20-24)(20-33)(21-31)(21-33)(22-28)(22-31)(23-38)(25-37)(26-35)(26-36)(27-28)(27-29)(29-36)(30-41)(30-42)(31-36)(32-39)(32-40)(33-35)(34-35)(34-43)(37-47)(38-49)(39-42)(39-48)(40-41)(40-47)(41-49)(42-50)(43-48)(43-50)(44-51)(45-52)(46-53)(49-54)(50-54)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 14 | — | 10.1039/d3dt04383e | 2024 |
| MCF-7 | 17 | — | 10.1039/d3dt04383e | 2024 |
| HEK293 | 67 | — | 10.1039/d3dt04383e | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Complex 3c also showed competency to induce apoptosis in MCF-7 cells through G2/M phase cell-cycle arrest in association with the generation of ample reactive oxygen species (ROS), eventually leading ...»