Info
| ID | 6200 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"O": 3, "N": 4} |
| Abbreviation | 3e |
| SMILES | [C-]#[O+].[C-]#[O+].[C-]#[O+].[Cl-].c1ccc2c(-c3nc4c5cccnc5c5ncccc5c4[nH]3)cccc2c1 |
TUCAN
C26H14N4O3Re/(1-31)(2-19)(3-32)(4-20)(5-22)(6-16)(7-15)(8-17)(9-25)(10-23)(11-21)(12-24)(13-18)(14-42)(15-22)(15-26)(16-17)(16-20)(17-29)(18-21)(18-28)(19-24)(19-27)(20-27)(21-31)(22-32)(23-24)(23-25)(25-30)(26-33)(26-36)(27-30)(28-34)(28-35)(29-30)(29-37)(31-41)(32-43)(33-35)(33-43)(34-36)(34-42)(35-41)(36-44)(37-42)(37-44)(38-45)(39-46)(40-47)(43-48)(44-48)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 18 | — | 10.1039/d3dt04383e | 2024 |
| MCF-7 | 26 | — | 10.1039/d3dt04383e | 2024 |
| HEK293 | 85 | — | 10.1039/d3dt04383e | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Complex 3c also showed competency to induce apoptosis in MCF-7 cells through G2/M phase cell-cycle arrest in association with the generation of ample reactive oxygen species (ROS), eventually leading ...»