Info
| ID | 6196 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"O": 3, "N": 4} |
| Abbreviation | 3a |
| SMILES | [C-]#[O+].[C-]#[O+].[C-]#[O+].[Cl-].c1ccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1 |
TUCAN
C22H12N4O3Re/(1-17)(2-16)(3-13)(4-18)(5-20)(6-21)(7-14)(8-19)(9-15)(10-25)(11-26)(12-36)(13-17)(13-23)(14-15)(14-22)(15-26)(16-18)(16-19)(17-25)(18-24)(19-21)(20-21)(20-24)(22-29)(22-30)(23-27)(23-28)(24-31)(25-37)(26-35)(27-29)(27-38)(28-30)(28-37)(29-36)(30-35)(31-36)(31-38)(32-39)(33-40)(34-41)(37-42)(38-42)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 41 | — | 10.1039/d3dt04383e | 2024 |
| HeLa | 64 | — | 10.1039/d3dt04383e | 2024 |
| HEK293 | 1.4e+02 | — | 10.1039/d3dt04383e | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Complex 3c also showed competency to induce apoptosis in MCF-7 cells through G2/M phase cell-cycle arrest in association with the generation of ample reactive oxygen species (ROS), eventually leading ...»