Info
| ID | 6149 |
| Metal | Re |
| Oxidation state | 1 |
| Charge | 1 |
| Donor atoms | {"N": 5, "O": 3} |
| Abbreviation | 3 |
| SMILES | COc1ccc2[nH]cc(-c3nc4c5cccnc5c5ncccc5c4[nH]3)c2c1.O.[C-]#[O+].[C-]#[O+].[C-]#[O+] |
TUCAN
C25H15N5O4Re/(1-27)(2-18)(3-39)(4-29)(5-39)(6-19)(7-39)(8-17)(9-21)(10-16)(11-28)(12-22)(13-20)(14-42)(15-43)(16-23)(16-40)(17-18)(17-24)(18-27)(19-21)(19-34)(20-22)(20-25)(21-40)(22-28)(23-26)(23-34)(24-30)(24-31)(25-32)(25-33)(26-29)(26-35)(27-41)(28-44)(29-43)(30-33)(30-42)(31-32)(31-41)(32-44)(33-45)(34-43)(35-42)(35-45)(36-46)(37-47)(38-48)(39-49)(40-49)(44-50)(45-50)(49-50)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| PC-3 | 0.32 | — | 10.1021/acs.inorgchem.3c00730 | 2023 |
| RPE-1 | 8.2 | — | 10.1021/acs.inorgchem.3c00730 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«for complex 6, a concentration-dependent induction of apoptosis was observed (Figure 11). However, the amount of apoptosis induction by 6 was very low, suggesting that apoptosis may not be a major pat...»