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Complex #6087 — Ir(3) [Ir12]

2D Structure

Structure
⬇ MOL V3000

Info

ID6087
MetalIr
Oxidation state3
Charge1
Donor atoms{"N": 4}
AbbreviationIr12
SMILESCOc1c[c-]c(-c2ccccn2)cc1.COc1c[c-]c(-c2ccccn2)cc1.COc1ccc(/N=C/c2ccccc2N)cc1

TUCAN

C38H34IrN4O3/(1-37)(2-44)(3-38)(4-67)(5-68)(6-55)(7-53)(8-69)(9-62)(10-43)(11-67)(12-46)(13-68)(14-56)(15-39)(16-68)(17-41)(18-69)(19-54)(20-69)(21-67)(22-49)(23-60)(24-52)(25-45)(26-40)(27-61)(28-50)(29-51)(30-48)(31-47)(32-42)(33-73)(34-73)(35-42)(35-58)(36-53)(36-57)(37-46)(37-70)(38-50)(38-59)(39-45)(39-64)(40-56)(40-63)(41-47)(41-71)(42-71)(43-48)(43-54)(44-49)(44-70)(45-50)(46-65)(47-58)(48-66)(49-65)(51-52)(51-57)(52-72)(53-72)(54-62)(55-56)(55-61)(57-63)(58-66)(59-60)(59-64)(60-75)(61-74)(62-76)(63-74)(64-73)(65-75)(66-76)(67-77)(68-78)(69-79)(70-77)(71-79)(72-78)(74-80)(75-80)(76-80)(79-80)

Measurements (5)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
HeLa11 10.1039/d3dt03700b 2024
A54916 10.1039/d3dt03700b 2024
HepG219 10.1039/d3dt03700b 2024
A549cisR19 10.1039/d3dt03700b 2024
BEAS-2B26 10.1039/d3dt03700b 2024

🧬 Cell Death Types (1)

Apoptosis high
«the complexes were observed to induce late apoptosis»