Info
| ID | 6087 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir12 |
| SMILES | COc1c[c-]c(-c2ccccn2)cc1.COc1c[c-]c(-c2ccccn2)cc1.COc1ccc(/N=C/c2ccccc2N)cc1 |
TUCAN
C38H34IrN4O3/(1-37)(2-44)(3-38)(4-67)(5-68)(6-55)(7-53)(8-69)(9-62)(10-43)(11-67)(12-46)(13-68)(14-56)(15-39)(16-68)(17-41)(18-69)(19-54)(20-69)(21-67)(22-49)(23-60)(24-52)(25-45)(26-40)(27-61)(28-50)(29-51)(30-48)(31-47)(32-42)(33-73)(34-73)(35-42)(35-58)(36-53)(36-57)(37-46)(37-70)(38-50)(38-59)(39-45)(39-64)(40-56)(40-63)(41-47)(41-71)(42-71)(43-48)(43-54)(44-49)(44-70)(45-50)(46-65)(47-58)(48-66)(49-65)(51-52)(51-57)(52-72)(53-72)(54-62)(55-56)(55-61)(57-63)(58-66)(59-60)(59-64)(60-75)(61-74)(62-76)(63-74)(64-73)(65-75)(66-76)(67-77)(68-78)(69-79)(70-77)(71-79)(72-78)(74-80)(75-80)(76-80)(79-80)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 11 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 16 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 19 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 19 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 26 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»