Info
| ID | 6086 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir11 |
| SMILES | COc1ccc(/N=C/c2ccccc2N)cc1.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C36H30IrN4O/(1-33)(2-58)(3-50)(4-37)(5-35)(6-42)(7-45)(8-43)(9-34)(10-39)(11-47)(12-40)(13-65)(14-54)(15-53)(16-41)(17-38)(18-49)(19-44)(20-52)(21-65)(22-48)(23-46)(24-60)(25-51)(26-36)(27-65)(28-59)(29-67)(30-67)(31-38)(31-55)(32-49)(32-56)(33-38)(33-50)(34-35)(34-37)(35-61)(36-45)(36-52)(37-58)(39-47)(39-64)(40-41)(40-62)(41-66)(42-49)(42-51)(43-50)(43-55)(44-51)(44-56)(45-63)(46-53)(46-66)(47-54)(48-54)(48-57)(52-60)(53-62)(55-61)(56-63)(57-59)(57-64)(58-69)(59-68)(60-70)(61-69)(62-68)(63-70)(64-67)(65-71)(66-71)(68-72)(69-72)(70-72)(71-72)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 10 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 14 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 17 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 18 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 25 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»