Info
| ID | 6085 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir10 |
| SMILES | COc1c[c-]c(-c2ccccn2)cc1.COc1c[c-]c(-c2ccccn2)cc1.Cc1ccc(/N=C/c2ccccc2N)cc1 |
TUCAN
C38H34IrN4O2/(1-62)(2-50)(3-49)(4-51)(5-69)(6-52)(7-55)(8-48)(9-57)(10-47)(11-40)(12-45)(13-41)(14-35)(15-69)(16-38)(17-56)(18-53)(19-54)(20-43)(21-63)(22-42)(23-35)(24-39)(25-64)(26-69)(27-35)(28-44)(29-46)(30-70)(31-70)(32-70)(33-73)(34-73)(35-61)(36-46)(36-58)(37-54)(37-60)(38-52)(38-58)(39-44)(39-68)(40-50)(40-65)(41-49)(41-59)(42-56)(42-66)(43-47)(43-72)(44-49)(45-51)(45-65)(46-71)(47-60)(48-53)(48-63)(50-61)(51-61)(52-71)(53-57)(54-72)(55-56)(55-64)(57-67)(58-66)(59-62)(59-68)(60-67)(62-74)(63-76)(64-75)(65-74)(66-75)(67-76)(68-73)(69-77)(70-78)(71-77)(72-78)(74-79)(75-79)(76-79)(78-79)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 13 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 16 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 19 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 19 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 28 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»