Info
| ID | 6084 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir9 |
| SMILES | Cc1ccc(/N=C/c2ccccc2N)cc1.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C36H30IrN4/(1-49)(2-34)(3-35)(4-44)(5-37)(6-45)(7-42)(8-47)(9-31)(10-39)(11-38)(12-53)(13-62)(14-50)(15-43)(16-48)(17-60)(18-61)(19-31)(20-41)(21-54)(22-46)(23-51)(24-36)(25-52)(26-40)(27-31)(28-55)(29-67)(30-67)(31-57)(32-37)(32-56)(33-48)(33-58)(34-37)(34-49)(35-36)(35-45)(36-60)(38-39)(38-57)(39-64)(40-41)(40-47)(41-55)(42-48)(42-51)(43-49)(43-56)(44-50)(44-52)(45-63)(46-51)(46-58)(47-59)(50-66)(52-61)(53-54)(53-64)(54-57)(55-65)(56-63)(58-66)(59-62)(59-65)(60-68)(61-69)(62-70)(63-68)(64-70)(65-67)(66-69)(68-71)(69-71)(70-71)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 10 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 14 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 17 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 18 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 25 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»