Info
| ID | 6083 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir8 |
| SMILES | CC(C)(C)c1ccc(/N=C/c2ccccc2N)cc1.COc1c[c-]c(-c2ccccn2)cc1.COc1c[c-]c(-c2ccccn2)cc1 |
TUCAN
C41H40IrN4O2/(1-61)(2-56)(3-78)(4-46)(5-62)(6-48)(7-41)(8-64)(9-41)(10-50)(11-41)(12-79)(13-54)(14-59)(15-57)(16-72)(17-78)(18-71)(19-49)(20-42)(21-42)(22-42)(23-73)(24-65)(25-79)(26-60)(27-79)(28-63)(29-55)(30-78)(31-47)(32-51)(33-53)(34-58)(35-43)(36-43)(37-52)(38-43)(39-82)(40-82)(41-70)(42-70)(43-70)(44-59)(44-66)(45-46)(45-69)(46-80)(47-56)(47-71)(48-61)(48-75)(49-50)(49-76)(50-67)(51-53)(51-77)(52-65)(52-76)(53-58)(54-60)(54-81)(55-61)(55-72)(56-62)(57-63)(57-80)(58-64)(59-81)(60-66)(62-74)(63-69)(64-68)(65-67)(66-74)(67-70)(68-73)(68-77)(69-75)(71-84)(72-83)(73-85)(74-84)(75-83)(76-85)(77-82)(78-87)(79-86)(80-87)(81-86)(83-88)(84-88)(85-88)(87-88)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 11 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 15 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 17 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 18 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 28 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»