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Complex #6083 — Ir(3) [Ir8]

2D Structure

Structure
⬇ MOL V3000

Info

ID6083
MetalIr
Oxidation state3
Charge1
Donor atoms{"N": 4}
AbbreviationIr8
SMILESCC(C)(C)c1ccc(/N=C/c2ccccc2N)cc1.COc1c[c-]c(-c2ccccn2)cc1.COc1c[c-]c(-c2ccccn2)cc1

TUCAN

C41H40IrN4O2/(1-61)(2-56)(3-78)(4-46)(5-62)(6-48)(7-41)(8-64)(9-41)(10-50)(11-41)(12-79)(13-54)(14-59)(15-57)(16-72)(17-78)(18-71)(19-49)(20-42)(21-42)(22-42)(23-73)(24-65)(25-79)(26-60)(27-79)(28-63)(29-55)(30-78)(31-47)(32-51)(33-53)(34-58)(35-43)(36-43)(37-52)(38-43)(39-82)(40-82)(41-70)(42-70)(43-70)(44-59)(44-66)(45-46)(45-69)(46-80)(47-56)(47-71)(48-61)(48-75)(49-50)(49-76)(50-67)(51-53)(51-77)(52-65)(52-76)(53-58)(54-60)(54-81)(55-61)(55-72)(56-62)(57-63)(57-80)(58-64)(59-81)(60-66)(62-74)(63-69)(64-68)(65-67)(66-74)(67-70)(68-73)(68-77)(69-75)(71-84)(72-83)(73-85)(74-84)(75-83)(76-85)(77-82)(78-87)(79-86)(80-87)(81-86)(83-88)(84-88)(85-88)(87-88)

Measurements (5)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
HeLa11 10.1039/d3dt03700b 2024
A54915 10.1039/d3dt03700b 2024
A549cisR17 10.1039/d3dt03700b 2024
HepG218 10.1039/d3dt03700b 2024
BEAS-2B28 10.1039/d3dt03700b 2024

🧬 Cell Death Types (1)

Apoptosis high
«the complexes were observed to induce late apoptosis»