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Complex #6082 — Ir(3) [Ir7]

2D Structure

Structure
⬇ MOL V3000

Info

ID6082
MetalIr
Oxidation state3
Charge1
Donor atoms{"N": 4}
AbbreviationIr7
SMILESCC(C)(C)c1ccc(/N=C/c2ccccc2N)cc1.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1

TUCAN

C39H36IrN4/(1-49)(2-48)(3-57)(4-59)(5-42)(6-45)(7-69)(8-44)(9-52)(10-50)(11-37)(12-56)(13-62)(14-37)(15-37)(16-55)(17-38)(18-38)(19-43)(20-58)(21-47)(22-70)(23-38)(24-71)(25-39)(26-54)(27-51)(28-53)(29-46)(30-60)(31-39)(32-63)(33-39)(34-61)(35-76)(36-76)(37-68)(38-68)(39-68)(40-44)(40-65)(41-50)(41-67)(42-45)(42-47)(43-51)(43-65)(44-57)(45-74)(46-52)(46-60)(47-69)(48-49)(48-72)(49-64)(50-59)(51-57)(52-75)(53-58)(53-59)(54-61)(54-62)(55-62)(55-73)(56-63)(56-64)(58-67)(60-70)(61-66)(63-72)(64-68)(65-74)(66-71)(66-73)(67-75)(69-77)(70-79)(71-78)(72-78)(73-76)(74-77)(75-79)(77-80)(78-80)(79-80)

Measurements (5)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
HeLa11 10.1039/d3dt03700b 2024
A54916 10.1039/d3dt03700b 2024
HepG218 10.1039/d3dt03700b 2024
A549cisR20 10.1039/d3dt03700b 2024
BEAS-2B30 10.1039/d3dt03700b 2024

🧬 Cell Death Types (1)

Apoptosis high
«the complexes were observed to induce late apoptosis»