Info
| ID | 6082 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir7 |
| SMILES | CC(C)(C)c1ccc(/N=C/c2ccccc2N)cc1.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C39H36IrN4/(1-49)(2-48)(3-57)(4-59)(5-42)(6-45)(7-69)(8-44)(9-52)(10-50)(11-37)(12-56)(13-62)(14-37)(15-37)(16-55)(17-38)(18-38)(19-43)(20-58)(21-47)(22-70)(23-38)(24-71)(25-39)(26-54)(27-51)(28-53)(29-46)(30-60)(31-39)(32-63)(33-39)(34-61)(35-76)(36-76)(37-68)(38-68)(39-68)(40-44)(40-65)(41-50)(41-67)(42-45)(42-47)(43-51)(43-65)(44-57)(45-74)(46-52)(46-60)(47-69)(48-49)(48-72)(49-64)(50-59)(51-57)(52-75)(53-58)(53-59)(54-61)(54-62)(55-62)(55-73)(56-63)(56-64)(58-67)(60-70)(61-66)(63-72)(64-68)(65-74)(66-71)(66-73)(67-75)(69-77)(70-79)(71-78)(72-78)(73-76)(74-77)(75-79)(77-80)(78-80)(79-80)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 11 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 16 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 18 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 20 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 30 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»