Info
| ID | 6081 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir6 |
| SMILES | Cc1ccc(/N=C/c2ccccc2[NH-])cc1.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C36H29IrN4/(1-48)(2-33)(3-34)(4-43)(5-36)(6-44)(7-41)(8-46)(9-38)(10-30)(11-52)(12-37)(13-61)(14-49)(15-42)(16-47)(17-59)(18-60)(19-30)(20-40)(21-53)(22-45)(23-50)(24-35)(25-51)(26-39)(27-30)(28-54)(29-66)(30-56)(31-36)(31-55)(32-47)(32-57)(33-36)(33-48)(34-35)(34-44)(35-59)(37-38)(37-56)(38-63)(39-40)(39-46)(40-54)(41-47)(41-50)(42-48)(42-55)(43-49)(43-51)(44-62)(45-50)(45-57)(46-58)(49-65)(51-60)(52-53)(52-63)(53-56)(54-64)(55-62)(57-65)(58-61)(58-64)(59-67)(60-68)(61-69)(62-67)(63-69)(64-66)(65-68)(66-70)(67-70)(68-70)(69-70)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 10 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 14 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 15 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 17 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 23 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»