Info
| ID | 6080 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir5 |
| SMILES | CC(C)(C)c1ccc(/N=C/c2ccccc2[NH-])cc1.FC(F)(F)c1c[c-]c(-c2ccccn2)cc1.FC(F)(F)c1c[c-]c(-c2ccccn2)cc1 |
TUCAN
C41H33F6IrN4/(1-49)(2-56)(3-67)(4-48)(5-44)(6-34)(7-57)(8-34)(9-34)(10-50)(11-35)(12-41)(13-39)(14-68)(15-43)(16-54)(17-52)(18-47)(19-51)(20-35)(21-66)(22-35)(23-55)(24-40)(25-53)(26-42)(27-46)(28-45)(29-36)(30-36)(31-58)(32-36)(33-75)(34-65)(35-65)(36-65)(37-44)(37-59)(38-47)(38-60)(39-41)(39-59)(40-48)(40-52)(41-63)(42-43)(42-70)(43-61)(44-63)(45-53)(45-55)(46-54)(46-60)(47-64)(48-69)(49-56)(49-71)(50-56)(50-57)(51-58)(51-61)(52-67)(53-72)(54-64)(55-68)(57-62)(58-70)(59-69)(60-72)(61-65)(62-66)(62-71)(63-73)(64-74)(66-77)(67-76)(68-78)(69-76)(70-77)(71-75)(72-78)(73-79)(73-80)(73-81)(74-82)(74-83)(74-84)(75-85)(76-85)(77-85)(78-85)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 11 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 14 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 14 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 16 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 25 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»