Info
| ID | 6079 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir4 |
| SMILES | CC(C)(C)c1ccc(/N=C/c2ccccc2[NH-])cc1.Fc1c[c-]c(-c2ccccn2)c(F)c1.Fc1c[c-]c(-c2ccccn2)c(F)c1 |
TUCAN
C39H31F4IrN4/(1-45)(2-50)(3-54)(4-38)(5-39)(6-41)(7-42)(8-32)(9-51)(10-61)(11-32)(12-52)(13-37)(14-48)(15-46)(16-53)(17-32)(18-33)(19-44)(20-33)(21-47)(22-43)(23-60)(24-40)(25-62)(26-49)(27-33)(28-34)(29-34)(30-34)(31-71)(32-59)(33-59)(34-59)(35-40)(35-55)(36-49)(36-56)(37-67)(37-68)(38-39)(38-48)(39-60)(40-68)(41-42)(41-64)(42-57)(43-45)(43-65)(44-51)(44-57)(45-50)(46-69)(46-70)(47-52)(47-53)(48-63)(49-70)(50-54)(51-64)(52-62)(53-66)(54-58)(55-63)(55-67)(56-66)(56-69)(57-59)(58-61)(58-65)(60-73)(61-72)(62-74)(63-73)(64-72)(65-71)(66-74)(67-76)(68-75)(69-77)(70-78)(71-79)(72-79)(73-79)(74-79)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 10 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 14 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 15 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 16 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 25 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»