Info
| ID | 6078 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir3 |
| SMILES | CC(C)(C)c1ccc(/N=C/c2ccccc2[NH-])cc1.Cc1c[c-]c(-c2ccccn2)cc1.Cc1c[c-]c(-c2ccccn2)cc1 |
TUCAN
C41H39IrN4/(1-57)(2-49)(3-74)(4-40)(5-76)(6-40)(7-50)(8-56)(9-42)(10-53)(11-60)(12-42)(13-75)(14-54)(15-42)(16-40)(17-48)(18-62)(19-41)(20-65)(21-64)(22-41)(23-43)(24-51)(25-55)(26-66)(27-43)(28-43)(29-63)(30-47)(31-59)(32-58)(33-41)(34-44)(35-52)(36-61)(37-44)(38-44)(39-81)(40-68)(41-72)(42-73)(43-73)(44-73)(45-49)(45-67)(46-56)(46-70)(47-62)(47-67)(48-50)(48-57)(49-68)(50-74)(51-52)(51-79)(52-53)(53-54)(54-69)(55-60)(55-78)(56-72)(57-77)(58-63)(58-64)(59-65)(59-70)(60-71)(61-66)(61-71)(62-68)(63-80)(64-76)(65-72)(66-78)(67-77)(69-75)(69-79)(70-80)(71-73)(74-82)(75-83)(76-84)(77-82)(78-83)(79-81)(80-84)(81-85)(82-85)(83-85)(84-85)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 12 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 14 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 16 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 16 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 27 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»