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Complex #6077 — Ir(3) [Ir2]

2D Structure

Structure
⬇ MOL V3000

Info

ID6077
MetalIr
Oxidation state3
Charge0
Donor atoms{"N": 4}
AbbreviationIr2
SMILESCC(C)(C)c1ccc(/N=C/c2ccccc2[NH-])cc1.COc1c[c-]c(-c2ccccn2)cc1.COc1c[c-]c(-c2ccccn2)cc1

TUCAN

C41H39IrN4O2/(1-55)(2-60)(3-77)(4-45)(5-47)(6-61)(7-40)(8-63)(9-40)(10-40)(11-77)(12-53)(13-58)(14-56)(15-70)(16-77)(17-71)(18-49)(19-48)(20-41)(21-41)(22-41)(23-72)(24-64)(25-78)(26-59)(27-78)(28-62)(29-46)(30-78)(31-54)(32-50)(33-52)(34-57)(35-42)(36-42)(37-51)(38-42)(39-81)(40-69)(41-69)(42-69)(43-45)(43-65)(44-58)(44-68)(45-79)(46-55)(46-70)(47-55)(47-73)(48-49)(48-75)(49-66)(50-52)(50-76)(51-64)(51-75)(52-57)(53-59)(53-79)(54-60)(54-71)(56-62)(56-80)(57-63)(58-80)(59-65)(60-61)(61-74)(62-68)(63-67)(64-66)(65-73)(66-69)(67-72)(67-76)(68-74)(70-82)(71-83)(72-84)(73-82)(74-83)(75-84)(76-81)(77-85)(78-86)(79-85)(80-86)(81-87)(82-87)(83-87)(84-87)

Measurements (5)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
HeLa11 10.1039/d3dt03700b 2024
A54914 10.1039/d3dt03700b 2024
A549cisR16 10.1039/d3dt03700b 2024
HepG217 10.1039/d3dt03700b 2024
BEAS-2B28 10.1039/d3dt03700b 2024

🧬 Cell Death Types (1)

Apoptosis high
«the complexes were observed to induce late apoptosis»