Info
| ID | 6077 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir2 |
| SMILES | CC(C)(C)c1ccc(/N=C/c2ccccc2[NH-])cc1.COc1c[c-]c(-c2ccccn2)cc1.COc1c[c-]c(-c2ccccn2)cc1 |
TUCAN
C41H39IrN4O2/(1-55)(2-60)(3-77)(4-45)(5-47)(6-61)(7-40)(8-63)(9-40)(10-40)(11-77)(12-53)(13-58)(14-56)(15-70)(16-77)(17-71)(18-49)(19-48)(20-41)(21-41)(22-41)(23-72)(24-64)(25-78)(26-59)(27-78)(28-62)(29-46)(30-78)(31-54)(32-50)(33-52)(34-57)(35-42)(36-42)(37-51)(38-42)(39-81)(40-69)(41-69)(42-69)(43-45)(43-65)(44-58)(44-68)(45-79)(46-55)(46-70)(47-55)(47-73)(48-49)(48-75)(49-66)(50-52)(50-76)(51-64)(51-75)(52-57)(53-59)(53-79)(54-60)(54-71)(56-62)(56-80)(57-63)(58-80)(59-65)(60-61)(61-74)(62-68)(63-67)(64-66)(65-73)(66-69)(67-72)(67-76)(68-74)(70-82)(71-83)(72-84)(73-82)(74-83)(75-84)(76-81)(77-85)(78-86)(79-85)(80-86)(81-87)(82-87)(83-87)(84-87)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 11 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 14 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 16 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 17 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 28 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»