Info
| ID | 6076 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir1 |
| SMILES | CC(C)(C)c1ccc(/N=C/c2ccccc2[NH-])cc1.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C39H35IrN4/(1-48)(2-47)(3-56)(4-58)(5-41)(6-44)(7-68)(8-43)(9-51)(10-49)(11-36)(12-55)(13-61)(14-36)(15-36)(16-54)(17-37)(18-37)(19-42)(20-57)(21-46)(22-69)(23-37)(24-70)(25-38)(26-53)(27-50)(28-52)(29-45)(30-59)(31-38)(32-62)(33-38)(34-60)(35-75)(36-67)(37-67)(38-67)(39-43)(39-64)(40-49)(40-66)(41-44)(41-46)(42-50)(42-64)(43-56)(44-73)(45-51)(45-59)(46-68)(47-48)(47-71)(48-63)(49-58)(50-56)(51-74)(52-57)(52-58)(53-60)(53-61)(54-61)(54-72)(55-62)(55-63)(57-66)(59-69)(60-65)(62-71)(63-67)(64-73)(65-70)(65-72)(66-74)(68-76)(69-78)(70-77)(71-77)(72-75)(73-76)(74-78)(75-79)(76-79)(77-79)(78-79)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 11 | — | 10.1039/d3dt03700b | 2024 |
| A549 | 16 | — | 10.1039/d3dt03700b | 2024 |
| A549cisR | 17 | — | 10.1039/d3dt03700b | 2024 |
| HepG2 | 17 | — | 10.1039/d3dt03700b | 2024 |
| BEAS-2B | 29 | — | 10.1039/d3dt03700b | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«the complexes were observed to induce late apoptosis»