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Complex #599 — Ru(2) [2c]

2D Structure

Structure
⬇ MOL V3000

Info

ID599
MetalRu
Oxidation state2
Charge1
Donor atoms{"N": 3}
Abbreviation2c
SMILESCc1ccc(C(C)C)cc1.NC(=S)n1nc(-c2ccccc2)cc1O.[Cl-]

TUCAN

C20H23N3ORuS/(1-30)(2-36)(3-40)(4-25)(5-31)(6-24)(7-34)(8-28)(9-33)(10-29)(11-35)(12-27)(13-25)(14-25)(15-26)(16-24)(17-24)(18-26)(19-26)(20-32)(21-44)(22-44)(23-47)(24-38)(25-40)(26-40)(27-41)(27-42)(28-29)(28-34)(29-37)(30-31)(30-38)(31-39)(32-36)(32-39)(33-34)(33-35)(35-37)(36-38)(37-41)(39-40)(41-46)(42-45)(42-47)(43-44)(43-45)(43-48)(45-46)(46-49)(47-49)

Measurements (33)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
NALM612— 10.3390/molecules28093969 2023
NALM612— 10.1039/c9ra08736b 2019
WM11519— 10.3390/molecules28093969 2023
NALM620— 10.3390/molecules28093969 2023
HEC-1-A24— 10.3390/molecules28093969 2023
WM11527— 10.1039/c9ra08736b 2019
WM11527— 10.3390/molecules28093969 2023
COLO-20527— 10.3390/molecules28093969 2023
HT-2930— 10.3390/molecules28093969 2023
MCF-730— 10.3390/molecules28093969 2023
LoVo32— 10.3390/molecules28093969 2023
COLO-20533— 10.3390/molecules28093969 2023
HEC-1-A40— 10.3390/molecules28093969 2023
LoVo43— 10.3390/molecules28093969 2023
SW62049— 10.3390/molecules28093969 2023
Hep3B52— 10.3390/molecules28093969 2023
HL6070— 10.3390/molecules28093969 2023
HeLa79— 10.3390/molecules28093969 2023
MCF-783— 10.3390/molecules28093969 2023
HL6086— 10.3390/molecules28093969 2023
HL6087— 10.1039/c9ra08736b 2019
SW62090— 10.3390/molecules28093969 2023
Hep3B1e+02— 10.3390/molecules28093969 2023
HeLa1.2e+02— 10.3390/molecules28093969 2023
Ishikawa1.2e+02— 10.3390/molecules28093969 2023
HT-291.3e+02— 10.3390/molecules28093969 2023
HCC381.3e+02— 10.3390/molecules28093969 2023
Ishikawa1.4e+02— 10.3390/molecules28093969 2023
Caco-21.7e+02— 10.3390/molecules28093969 2023
A5491.9e+02— 10.3390/molecules28093969 2023
Caco-2—— 10.3390/molecules28093969 2023
A549—— 10.3390/molecules28093969 2023
HCC38—— 10.3390/molecules28093969 2023

🧬 Cell Death Types (1)

Apoptosis high
«Microscopic analysis showed that ruthenium derivatives induce apoptosis in cancer cells.»

Source-assisted 2D generator

Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.

experimental validation surface
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.