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Complex #5956 — Ir(3) [Ir-4]

2D Structure

Structure
⬇ MOL V3000

Info

ID5956
MetalIr
Oxidation state3
Charge1
Donor atoms{"N": 4}
AbbreviationIr-4
SMILES[c-]1c(-c2ccccn2)sc2ccccc12.[c-]1c(-c2ccccn2)sc2ccccc12.c1cnc2c(c1)ccc1cccnc12

TUCAN

C38H24IrN4S2/(1-51)(2-32)(3-28)(4-41)(5-53)(6-30)(7-31)(8-40)(9-33)(10-44)(11-29)(12-27)(13-45)(14-38)(15-39)(16-37)(17-52)(18-54)(19-35)(20-34)(21-42)(22-36)(23-43)(24-46)(25-47)(25-59)(26-50)(26-60)(27-35)(27-48)(28-29)(28-31)(29-55)(30-38)(30-47)(31-52)(32-38)(32-40)(33-41)(33-51)(34-39)(34-54)(35-49)(36-39)(36-58)(37-43)(37-50)(40-61)(41-48)(42-45)(42-49)(43-46)(44-46)(44-62)(45-53)(47-61)(48-56)(49-57)(50-62)(51-63)(52-64)(53-65)(54-66)(55-59)(55-64)(56-57)(56-63)(57-65)(58-60)(58-66)(59-67)(60-68)(61-67)(62-68)(63-69)(64-69)(65-69)(66-69)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A54918 10.1016/j.jinorgbio.2022.11205... 2023
A549cisR35 10.1016/j.jinorgbio.2022.11205... 2023
LO274 10.1016/j.jinorgbio.2022.11205... 2023

🧬 Cell Death Types (1)

Apoptosis high
«The flow cytometry investigations demonstrated that Ir-1 and Ir-3 can arrest the cell cycle in S phase and induce the cell death through apoptosis process.»