Info
| ID | 5935 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | Ir9 |
| SMILES | Cc1c(C)c(C)[c-](C)c1C.Cc1ccc(-n2c(-c3[c-]cccc3)nc3c4ccccc4c4ccccc4c32)cc1.[Cl-] |
TUCAN
C38ClIrN2/(1-24)(2-25)(3-26)(4-29)(5-31)(6-32)(7-8)(7-18)(8-27)(9-11)(9-33)(10-22)(10-37)(11-21)(12-17)(12-20)(13-23)(13-37)(14-17)(14-34)(15-16)(15-21)(16-33)(18-19)(19-30)(20-28)(22-29)(23-29)(24-25)(24-26)(25-31)(26-32)(27-30)(27-35)(28-34)(28-36)(30-34)(31-32)(33-38)(35-36)(35-39)(36-40)(37-40)(38-39)(38-40)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 66 | — | 10.1016/j.jinorgbio.2024.11261... | 2024 |
| BEAS-2B | 70 | — | 10.1016/j.jinorgbio.2024.11261... | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Western blotting further confirmed that complexes could induce A549 cell apoptosis through the lysosomal-mitochondrial anticancer pathway»