Info
| ID | 5927 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ir1 |
| SMILES | Cc1c(C)c(C)[c-](C)c1C.Cc1ccc(-n2c(-c3ccc(F)cc3)nc3c4cccnc4c4ncccc4c32)cc1.[Cl-] |
TUCAN
C36H32FIrN4/(1-33)(2-33)(3-33)(4-34)(5-34)(6-34)(7-35)(8-35)(9-39)(10-45)(11-46)(12-38)(13-61)(14-40)(15-41)(16-47)(17-38)(18-50)(19-43)(20-44)(21-48)(22-60)(23-49)(24-38)(25-42)(26-35)(27-36)(28-36)(29-36)(30-37)(31-37)(32-37)(33-52)(34-53)(35-54)(36-57)(37-58)(38-59)(39-44)(39-68)(40-41)(40-59)(41-66)(42-48)(42-68)(43-45)(43-51)(44-55)(45-60)(46-47)(46-61)(47-56)(48-55)(49-50)(49-59)(50-66)(51-62)(51-63)(52-53)(52-54)(53-57)(54-58)(55-67)(56-64)(56-65)(57-58)(60-69)(61-72)(62-64)(62-70)(63-65)(63-69)(64-71)(65-72)(66-70)(67-70)(67-71)(68-73)(71-74)(72-74)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | — | — | 10.1016/j.jinorgbio.2024.11261... | 2024 |
| BEAS-2B | — | — | 10.1016/j.jinorgbio.2024.11261... | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Western blotting further confirmed that complexes could induce A549 cell apoptosis through the lysosomal-mitochondrial anticancer pathway»