Info
| ID | 5926 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 6} |
| Abbreviation | Ir-CN |
| SMILES | N#Cc1ccc(-c2ccnc(-c3cc(-c4ccc(C#N)cc4)ccn3)c2)cc1.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C46H30IrN6/(1-37)(2-39)(3-69)(4-72)(5-38)(6-33)(7-36)(8-35)(9-46)(10-43)(11-47)(12-41)(13-48)(14-40)(15-45)(16-50)(17-70)(18-55)(19-52)(20-51)(21-53)(22-42)(23-54)(24-57)(25-44)(26-56)(27-58)(28-34)(29-71)(30-49)(31-33)(31-59)(32-34)(32-60)(33-38)(34-53)(35-39)(35-69)(36-37)(36-38)(37-59)(39-46)(40-47)(40-60)(41-43)(41-61)(42-62)(42-73)(43-64)(44-66)(44-74)(45-50)(45-61)(46-75)(47-53)(48-54)(48-72)(49-54)(49-76)(50-64)(51-62)(51-70)(52-55)(52-65)(55-63)(56-58)(56-65)(57-66)(57-71)(58-63)(59-75)(60-76)(61-62)(63-66)(64-67)(65-68)(67-77)(68-78)(69-79)(70-80)(71-81)(72-82)(73-74)(73-80)(74-81)(75-79)(76-82)(79-83)(80-83)(81-83)(82-83)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 40 | — | 10.1016/j.jphotobiol.2023.1128... | 2024 |
| MCF-7 | 72 | — | 10.1016/j.jphotobiol.2023.1128... | 2024 |
| MCF-10A | 72 | — | 10.1016/j.jphotobiol.2023.1128... | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«This mitochondrial imbalance and apoptotic induction were dually confirmed through various apoptotic assays including Annexin V staining and by mapping the molecular level changes through surface-enha...»