Info
| ID | 591 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 2} |
| Abbreviation | 1 |
| SMILES | O=C1C=CC(=O)[N-]1.[C-]#[O+].[C-]#[O+].c1cc[cH-]c1 |
TUCAN
C11NO4Ru/(1-2)(1-3)(2-4)(3-5)(4-5)(6-7)(6-10)(7-11)(8-14)(9-15)(10-12)(10-13)(11-12)(11-16)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HL60 | 5.6 | — | 10.1002/aoc.6595 | 2022 |
| HL60 | 6.4 | — | 10.1039/d2dt04083b | 2023 |
| PBMCs | 53 | — | 10.1002/aoc.6595 | 2022 |
| PBM | 75 | — | 10.1039/d2dt04083b | 2023 |
| HL-60/DR | 2.4e+02 | — | 10.1039/d2dt04083b | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«These complexes also induced apoptosis in HL-60 cells.»