Info
| ID | 59 |
| Metal | Ru |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"S": 1, "O": 1, "N": 3} |
| Abbreviation | 2 |
| SMILES | CS(C)=O.Nc1ccccc1-c1nc2ccccc2[nH]1.[Cl-].[Cl-].[Cl-] |
TUCAN
C15H17N3ORuS/(1-24)(2-25)(3-23)(4-31)(5-31)(6-22)(7-18)(8-20)(9-19)(10-21)(11-31)(12-32)(13-32)(14-32)(15-34)(16-33)(17-33)(18-19)(18-25)(19-27)(20-21)(20-23)(21-22)(22-29)(23-28)(24-25)(24-26)(26-27)(26-30)(27-33)(28-29)(28-34)(29-35)(30-34)(30-35)(31-37)(32-37)(35-38)(36-37)(37-38)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 2.3e+02 | — | 10.3390/molecules25184284 | 2020 |
| Caco-2 | 2.5e+02 | — | 10.3390/molecules25184284 | 2020 |
| THLE-2 | 2.5e+03 | — | 10.3390/molecules25184284 | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«An apoptosis mechanism was determined by the observation of increased Bax and caspase 3 and decreased Bcl2 expression.»