Info
| ID | 5867 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | Ir5amido |
| SMILES | Cc1c(C)c(C)[c-](C)c1C.Cc1cc(C)c(CC([N-]c2c(C(C)C)cccc2C(C)C)c2ccccn2)c(C)c1 |
TUCAN
C38H50IrN2/(1-59)(2-55)(3-55)(4-83)(5-59)(6-64)(7-59)(8-55)(9-52)(10-52)(11-52)(12-53)(13-53)(14-53)(15-54)(16-54)(17-54)(18-61)(19-61)(20-61)(21-62)(22-62)(23-56)(24-56)(25-70)(26-56)(27-57)(28-51)(29-63)(30-85)(31-57)(32-69)(33-51)(34-51)(35-84)(36-71)(37-88)(38-57)(39-66)(40-58)(41-68)(42-58)(43-60)(44-71)(45-60)(46-65)(47-58)(48-67)(49-60)(50-62)(51-72)(52-73)(53-74)(54-75)(55-83)(56-83)(57-84)(58-79)(59-80)(60-84)(61-76)(62-82)(63-72)(63-80)(64-70)(64-77)(65-69)(65-85)(66-69)(66-87)(67-70)(67-81)(68-79)(68-80)(71-78)(71-88)(72-78)(73-74)(73-75)(74-76)(75-82)(76-82)(77-83)(77-86)(78-79)(81-84)(81-86)(85-89)(86-90)(87-88)(87-89)(88-90)(89-91)(90-91)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 19 | — | 10.1021/acs.inorgchem.4c05599 | 2025 |
| HeLa | 20 | — | 10.1021/acs.inorgchem.4c05599 | 2025 |
| A549cisR | 24 | — | 10.1021/acs.inorgchem.4c05599 | 2025 |
| BEAS-2B | 27 | — | 10.1021/acs.inorgchem.4c05599 | 2025 |
🧬 Cell Death Types (1)
Apoptosis
high
«pyridyl-amine complexes induced apoptosis»