Info
| ID | 5864 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 3} |
| Abbreviation | 9 |
| SMILES | Cc1c(C)c(C)[c-](C)c1C.[Cl-].[c-]1cccc2c1c1ncccc1c1nccnc21 |
TUCAN
C25H23IrN3/(1-24)(2-24)(3-24)(4-25)(5-25)(6-25)(7-26)(8-45)(9-44)(10-32)(11-33)(12-43)(13-30)(14-31)(15-34)(16-26)(17-26)(18-27)(19-27)(20-27)(21-28)(22-28)(23-28)(24-36)(25-37)(26-38)(27-39)(28-40)(29-32)(29-42)(30-32)(30-34)(31-33)(31-35)(33-45)(34-41)(35-46)(35-47)(36-37)(36-38)(37-39)(38-40)(39-40)(41-42)(41-48)(42-47)(43-44)(43-49)(44-50)(45-51)(46-48)(46-50)(47-51)(48-49)(50-52)(51-52)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 8.7 | 5.3 | 10.1021/acs.jmedchem.3c01276 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Consequently, cell death by apoptosis and secondary necrosis is activated.»