home← all complexes D-MPNN

Complex #5860 — Ir(3) [5]

2D Structure

Structure
⬇ MOL V3000

Info

ID5860
MetalIr
Oxidation state3
Charge1
Donor atoms{"N": 6}
Abbreviation5
SMILESCc1c(C)c(C)[c-](C)c1C.[c-]1cccc2c1c1ncccc1c1nc3ccccc3nc21.c1cn(CCN2CCCCC2)cn1

TUCAN

C39H42IrN6/(1-43)(2-43)(3-43)(4-44)(5-44)(6-55)(7-54)(8-53)(9-52)(10-72)(11-72)(12-57)(13-51)(14-58)(15-75)(16-58)(17-49)(18-56)(19-71)(20-50)(21-73)(22-60)(23-75)(24-44)(25-45)(26-45)(27-45)(28-46)(29-46)(30-46)(31-47)(32-47)(33-69)(34-59)(35-73)(36-74)(37-59)(38-74)(39-70)(40-60)(41-81)(42-47)(43-61)(44-62)(45-63)(46-64)(47-65)(48-55)(48-66)(49-50)(49-77)(50-57)(51-57)(51-79)(52-56)(52-67)(53-54)(53-68)(54-55)(56-71)(58-60)(58-72)(59-60)(59-75)(61-62)(61-63)(62-64)(63-65)(64-65)(66-68)(66-78)(67-78)(67-80)(68-76)(69-70)(69-85)(70-84)(71-86)(72-83)(73-74)(73-83)(74-84)(75-83)(76-80)(76-82)(77-79)(77-82)(78-86)(79-87)(80-87)(81-84)(81-85)(85-88)(86-88)(87-88)

Measurements (2)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A5490.830.39 10.1021/acs.jmedchem.3c01276 2024
A5490.830.52 10.1021/acs.jmedchem.3c01276 2024

🧬 Cell Death Types (1)

Apoptosis high
«Consequently, cell death by apoptosis and secondary necrosis is activated.»